Fig. 4
From: Targeting Ezh2 could overcome docetaxel resistance in prostate cancer cells
MiR-101-3p and miR-138-5p were involved in Doc resistance by targeting Ezh2 a. MiR-101-3p and miR-138-5p were predicated to target Ezh2. b. MiR-101-3p and miR-138-5p were reduced in LNCaP DocR cells and 22Rv1 DocR cells. c. MiR-101-3p and miR-138-5p could reduce Ezh2. GAPDH was served as loading control. d. MiR-101-3p and miR-138-5p inhibited the sphere forming ability of DocR cells. e, f. MiR-101-3p and miR-138-5p restored Doc sensitivity of LNCaP DocR cells (e) and 22Rv1 DocR cells (f). G. Mechanistic depiction of how Ezh2 plays role in the development of Doc resistance. P* < 0.05