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Fig. 2 | BMC Cancer

Fig. 2

From: Targeting Ezh2 could overcome docetaxel resistance in prostate cancer cells

Fig. 2

Cancer stem cells were highly enriched in DocR cells. A-B. qPCR results showed that cancer stem cell markers (CD44, Nanog, Sox2) were highly induced in LNCaP DocR cells (a) and 22Rv1 DocR cells (b) compared to their corresponding parental cells. GAPDH was used as control. c. Top, representative images showing that the population of cancer stem cells was enriched in LNCaP DocR and 22Rv1 DocR cells, monitored by sphere formation assay. Bottom, statistical analysis of spheres. d. Top, representative images revealing that Ezh2 overexpressing cells had more cancer stem cells compared to vector bearing cells. Bottom, statistical analysis of spheres. P* < 0.05

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