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Table 4 Reasons for treatment discontinuation of patients with OS ≥24 versus < 24 months in the axitinib titration arm

From: Patients with metastatic renal cell carcinoma who benefit from axitinib dose titration: analysis from a randomised, double-blind phase II study

Reason for treatment discontinuation, n (%)

OS ≥24 months n = 33a

OS < 24 months n = 20b

Objective progression or relapse

17 (52)

16 (80)

Adverse event

5 (15)

2 (10)

Death

1 (3)

1 (5)

Global deterioration of health status

0

1 (5)

Patient refusal to continue treatment for reason other than adverse event

1 (3)

0

Total

24 (73)

20 (100)

  1. Abbreviation: OS overall survival
  2. aIncluding 9 patients still on treatment
  3. bExcluded 3 patients who were censored < 24 months in OS