Table 1 Patients’ demographics
Variable | Dose level 1 (N = 3) | Dose level − 1 (N = 6) | Total (N = 9) |
|---|---|---|---|
Age [Years] | |||
 N | 3 | 6 | 9 |
 Mean (SD) | 62.00 (21.63) | 60.17 (7.31) | 60.78 (12.30) |
 Min | 38.0 | 51.0 | 38.0 |
 Median | 68.00 | 59.00 | 60.00 |
 Max | 80.0 | 71.0 | 80.0 |
 Missing | 0 | 0 | 0 |
Gender | |||
 Female | 1 (33.33%) | 3 (50.00%) | 4 (44.44%) |
 Male | 2 (66.67%) | 3 (50.00%) | 5 (55.56%) |
Ethnicity | |||
 Caucasian | 3 (100.00%) | 6 (100.00%) | 9 (100.00%) |
Primary tumour | |||
 Intrahepathic tumour | 3 (100.00%) | 3 (50.00%) | 6 (66.67%) |
 Extrahepatic tumour | 0 (0.00%) | 3 (50.00%) | 3 (33.33%) |
ECOG | |||
 0 | 2 (66.67%) | 2 (33.33%) | 4 (44.44%) |
 1 | 1 (33.33%) | 4 (66.67%) | 5 (55.56%) |
Metastatic disease | 3 (100.00%) | 6 (100.00%) | 9 (100.00%) |
Target lesions | |||
 Primary tumour | 1 (14.29%) | 1 (10.00%) | 2 (11.76%) |
 Liver | 3 (42.86%) | 3 (30.00%) | 6 (35.29%) |
 Lung | 2 (28.57%) | 2 (20.00%) | 4 (23.53%) |
 Other lymph nodes | 1 (14.29%) | 0 (0.00%) | 1 (5.88%) |
 Peritoneum | 0 (0.00%) | 1 (10.00%) | 1 (5.88%) |
 Soft tissues | 0 (0.00%) | 1 (10.00%) | 1 (5.88%) |
 Others | 0 (0.00%) | 2 (20.00%) | 2 (11.76%) |