High Oct4 expression: implications in the pathogenesis of neuroblastic tumours

BMC Cancer

Table 2 Relationship between Oct expression and different survival-related parameters

Survival	Oct4 group (N)	Mean Oct4⁺ percentage	Rate of patients with event	Survival mean (months)	Survival at 5 years (%)	p-value
EFS	Low (433)	0.62	0.30	141.4 ± 5.3	67.1 ± 2.5	0.003
EFS	High (80)	19.84	0.49	77.1 ± 7.3	49.3 ± 5.8	0.003
OS	Low (433)	0.63	0.23	176.0 ± 8.5	75.2 ± 2.3	0.029
OS	High (80)	20.32	0.38	103.3 ± 7.6	59.8 ± 5.8	0.029

The events considered in EFS are both relapses and deaths while in OS only deaths are considered events. Rate of patients with event represents the fraction of relapsed or deceased patients of the total. Mean Oct4⁺ cell percentage values correspond to the mean proportion of Oct4⁺ cells presented in each Oct4 tumour group. The mean survival values are represented as the mean survived months without any event occurrence ± error. The 5-year cumulative survival indicates the percentage of patients without event at 5 years after the diagnosis ± error. All these parameters are considered for the Oct4⁺ cell percentage groups in EFS and OS. Statistical significance is shown as the obtained p-values (p-value< 0.050). N Total number of patients

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