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Fig. 4 | BMC Cancer

Fig. 4

From: Differences in tumor microenvironments between primary lung tumors and brain metastases in lung cancer patients: therapeutic implications for immune checkpoint inhibitors

Fig. 4

Kaplan–Meier plots for lung cancer patients with adenocarcinoma histology in cohort 2 according to a the amount of CD3+ TILs, b PD1+ TILs, and c the PD-L1 H-score in brain metastatic tissue. Overall survival was measured from the date of surgery until either death due to any cause or the last follow-up date. The cutoff-points were arbitrarily set to the median value of each variable. The significance of differences in survival curves were compared using a log-rank test. Abbreviations: TIL, tumor-infiltrating lymphocyte; PD-1, programmed cell death-1; PD-L1, programmed cell death ligand-1

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