From: Radium-223 in asymptomatic patients with castration-resistant prostate cancer and bone metastases treated in an international early access program
Radium-223 injections
Asymptomatic N = 135
Symptomatic N = 548
Median (range)
6 (1–6)
Only 1
4 (3)
33 (6)
Only 2
3 (2)
40 (7)
Only 3
5 (4)
59 (11)
Only 4
13 (10)
Only 5
14 (10)
57 (10)
All 6
96 (71)
300 (55)