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Fig. 3 | BMC Cancer

Fig. 3

From: A phase II trial of recombinant MAGE-A3 protein with immunostimulant AS15 in combination with high-dose Interleukin-2 (HDIL2) induction therapy in metastatic melanoma

Fig. 3

Changes in immune checkpoint expression of peripheral blood regulatory T cells with therapy. Compared to responders, non-responders show a relative increase in the expression of multiple immune checkpoint molecules on regulatory T cells on treatment including [41BB (p = 0.04), CTLA4 (p = 0.01), and LAG3 (p = 0.02)]

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