Table 1 Detection rates in the high-risk population using different screening protocols
High-risk population/ Reduced population(%) | CRC | Advanced neoplasm | Adenoma | Neoplasm | |||||
|---|---|---|---|---|---|---|---|---|---|
number(%) | OR(95% CI) | number(%) | OR(95% CI) | number(%) | OR(95% CI) | number(%) | OR(95% CI) | ||
Scenario A | 4075/0 | 39(100.0) | 1.0 | 181(100.0) | 1.0 | 359(100.0) | 1.0 | 524(100.0) | 1.0 |
Scenario B | 3090/985(24.2) | 39(100.0) | 1.32(0.85–2.07) | 161(89.0) | 1.18(0.95–1.47) | 308(85.8) | 1.15(0.98–1.35) | 441(84.2) | 1.13(0.98–1.29) |
Scenario C | 3832/243(6.00) | 39(100.0) | 1.04(0.66–1.62) | 171(94.5) | 1.01(0.81–1.24) | 340(94.7) | 1.01(0.86–1.18) | 495(94.5) | 1.01(0.88–1.15) |
Scenario D | 3928/147(3.61) | 39(100.0) | 1.04(0.66–1.62) | 180(99.4) | 1.03(0.84–1.28) | 358(99.8) | 1.04(0.89–1.21) | 517(98.7) | 1.03(0.90–1.17) |
Scenario E | 3357/718(17.6) | 39(100.0) | 1.22(0.78–1.90) | 172(95.0) | 1.16(0.94–1.44) | 327(91.1) | 1.12(0.95–1.31) | 476(90.1) | 1.12(0.98–1.28) |
Scenario F | 1762/2313(56.8) | 39(100.0) | 2.34(1.50–3.66) | 127(70.2) | 1.67(1.32–2.11) | 211(58.8) | 1.41(1.18–1.69) | 296(56.5) | 1.37(1.17–1.60) |
Scenario G | 2642/1433(35.2) | 11(28.2) | 0.43(0.22–0.85) | 78(43.1) | 0.65(0.50–0.86) | 189(52.3) | 0.80(0.66–0.96) | 341(65.1) | 1.00(0.87–1.16) |