A phase II randomized controlled trial of three exercise delivery methods in men with prostate cancer on androgen deprivation therapy

Table 3 Between group efficacy outcomes

Outcomes	Group-supervised versus PT	Home-based versus PT	Non-inferiority margin	Probability of inferiority of Group-supervised to PT^a	Probability of inferiority of Home-based to PT^a
Quality of Life and Fatigue
FACT-G	−1.7 (−8.7 to 5.4)	−2.9 (−9.7 to 3.8)	4 points	25.6%	37.9%
FACT-F	1.5 (−3.9 to 6.6)	−0.5 (−5.9 to 4.8)	3 points	4.9%	17.6%
FACT-P	−1.4 (−5.4 to 2.6)	−4.3 (− 8.1 to −0.5)	3 points	20.9%	74.4%
Physical Fitness
VO₂ peak	− 0.7 (− 3.2 to 1.8)	− 1.8 (−4.2 to 0.6)	2.5 mL/kg/min	8.2%	26.7%
Grip strength	−0.3 (− 3.3 to 2.7)	− 3.4 (−6.3 to − 0.6)	4.5 kg	0.2%	23.3%
Sit-to-stand	0.7 (− 4.3 to 5.5)	1.4 (− 3.3 to 5.9)	4 repetitions	3.1%	1.1%

Note: The above values are mean differences between baseline and 6 months with 95% confidence intervals in parentheses. The reference group is the personal training arm
FACT Functional Assessment of Cancer Therapy (G general, F fatigue subscale, P prostate); PT personal training
^aThe Bayesian posterior probability of inferiority is calculated as the probability that the mean outcome in the comparator arm is lower than that in the personal training arm by at least the specified non-inferiority margin. See text for more details

ISSN: 1471-2407