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Table 3 Between group efficacy outcomes

From: A phase II randomized controlled trial of three exercise delivery methods in men with prostate cancer on androgen deprivation therapy

Outcomes Group-supervised versus PT Home-based versus PT Non-inferiority margin Probability of inferiority of Group-supervised to PTa Probability of inferiority of Home-based to PTa
Quality of Life and Fatigue
 FACT-G −1.7 (−8.7 to 5.4) −2.9 (−9.7 to 3.8) 4 points 25.6% 37.9%
 FACT-F 1.5 (−3.9 to 6.6) −0.5 (−5.9 to 4.8) 3 points 4.9% 17.6%
 FACT-P −1.4 (−5.4 to 2.6) −4.3 (− 8.1 to −0.5) 3 points 20.9% 74.4%
Physical Fitness
 VO2 peak − 0.7 (− 3.2 to 1.8) − 1.8 (−4.2 to 0.6) 2.5 mL/kg/min 8.2% 26.7%
 Grip strength −0.3 (− 3.3 to 2.7) − 3.4 (−6.3 to − 0.6) 4.5 kg 0.2% 23.3%
 Sit-to-stand 0.7 (− 4.3 to 5.5) 1.4 (− 3.3 to 5.9) 4 repetitions 3.1% 1.1%
  1. Note: The above values are mean differences between baseline and 6 months with 95% confidence intervals in parentheses. The reference group is the personal training arm
  2. FACT Functional Assessment of Cancer Therapy (G general, F fatigue subscale, P prostate); PT personal training
  3. aThe Bayesian posterior probability of inferiority is calculated as the probability that the mean outcome in the comparator arm is lower than that in the personal training arm by at least the specified non-inferiority margin. See text for more details