Table 3 Between-group differences and within-group changes over time on primary and secondary outcomes in participants of the Quality of Life in Motion study
| Â | Between-group differences intervention group versus control group | Within group changes over time per study group | ||
|---|---|---|---|---|
Short-term intervention effects % | Long-term intervention effects % | Intervention group ∞ | Control group ∞ | |
β (95% CI) | β (95% CI) | β (95% CI) | β (95% CI) | |
Primary outcomes | ||||
 VO2peak, (ml.kg.min−1) | −0.6 (−3.1; 2.0) | − 0.6 (− 3.6; 2.5) | 2.1 (− 0.4; 4.5) | 2.0 (− 0.04; 4.1) |
 Upper body muscle strength (N) | −20.4 (− 47.4; 6.5) | 4.5 (− 21.3; 30.3) | 36.8 (12.6; 60.9)* | 11.8 (−8.7; 32.4) |
 Lower body muscle strength (N) | 22.7 (− 19.8; 65.2) | 56.5 (8.5; 104.5)* | 49.1 (14.1; 84.0)* | 15.3 (−24.3; 54.9) |
Secondary outcomes | ||||
 Physical activity (cpm) | 29.2 (−6.2; 64.8) | 8.2 (−44.3; 60.7) | 21.9 (−25.0; 68.9) | 42.9 (8.4; 77.5)* |
 BMD lumbar spine (g/cm2) | −0.001 (− 0.03; 0.02) | 0.007 (− 0.02; 0.03) | 0.04 (0.01; 0.07)** | 0.03 (0.02; 0.04)** |
 % fat mass | 0.6 (−0.7; 2.0) | 0.6 (−1.3; 2.5) | 0.6 (−0.5; 1.7) | 0.6 (− 0.4; 1.6) |
 General HrQoL | 1.6 (−5.0; 8.2) | −2.5 (−9.1; 4.1) | 5.6 (0.1; 11.0)* | 9.7 (4.6; 14.8)** |
 Fatigue | −1.6 (−7.5; 4.3) | − 1.8 (− 9.8; 6.2) | 3.7 (− 1.8; 9.3) | 4.0 (− 1.2;9.2) |
Extra outcomes used in mediation analysis | ||||
 Depressive symptoms | 5.0 (−6.1; 16.1) | 1.1 (− 11.3; 13.5) | −1.1 (− 2.0; 1.6) | −1.3 (− 2.4; − 0.2)* |
 Athletic competence | −1.3 (− 10.7; 8.1) | 9.3 (− 4.4; 23.1) | 10.1 (− 4.8; 25.0) | −5.2 (− 13.7; 3.4) |
 Global self-worth | 0.04 (− 12.5; 12.6) | 0.8 (− 12.7; 14.3) | 7.5 (− 1.9; 16.8) | 4.6 (− 3.7; 12.8) |
 Total problems | 6.8 (− 4.8; 18.4) | 3.4 (− 12.1; 18.8) | −0.4 (− 5.0; 4.1) | − 0.5 (− 4.0; 3.1) |