Fig. 6

Propofol suppressed Wnt/β-catenin and mTOR signaling pathways in A549 cells by down-regulating miR-372. After 8 μg/mL propofol treatment and/or miR-372 mimic (or miR-372 inhibitor) transfection, the protein expressions of (a) Wnt3a, p-β-catenin, t-β-catenin, (b) p-p70S6K, t-p70S6K, p-mTOR and t-mTOR in A549 cells were evaluated using western blotting. *P < 0.05, **P < 0.01, ***P < 0.001