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Table 4 Prognostic factors in patients treated with chemotherapy

From: Safety and efficacy of cytotoxic chemotherapy in hepatocellular carcinoma after first-line treatment with sorafenib

Prognostic factors

Median OS months (95%CI)

p univariate

p multivariate

Child-Pugh classification

 A

8.31 (2.72-9.88)

0.0251

0.524

 B-C

3.51 (0.52-14.12)

  

ECOG performance status

 0-1

9.36 (2.79 – 18.26)

<0.001

0.007

 2-3

1.08 (0.36- 2.01)

  

Best response to sorafenib

Progressive disease

2.73 (1.48-6.31)

0.0035

0.003

Disease control

9.89 (8.04-14.13)

  
  1. OS: overall survival; 95%CI: 95% confidence interval; ECOG: Eastern Cooperative Oncology Group