Fig. 6
a Boxplot correlation between pathologic response (pathologic complete response or non-complete pathologic response) and PID score from the neoadjuvant study. Boxplot A.i. is PID/cell vs. pathologic response and boxplot A.ii. is PID/ ROI100μm2 vs. pathologic response. The black diamonds represent the mean PID score for both categories. The black circles represent the PID score outliers in both categories that are less than or greater than 1.5 times the lower and upper interquartile range limits, respectively. Boxplot A.i. produced a p value = 0.011 and boxplot A.ii. produced a p value = 0.048 from a paired t-test. b Boxplot correlation between RCB class (0 (pCR), 1, 2 and 3) and PID from the neoadjuvant study. Boxplot B.i. is PID/cell vs. RCB class and boxplot B.ii. is PID/ROI100μm2 vs. RCB class. The black diamonds represent the mean PID score for each RCB class. The black circles represent the PID score outliers in each RCB class that are less than or greater than 1.5 times the lower and upper interquartile range limits, respectively. Boxplot B.i. produced a p value of 0.026 and an R2 correlation value of 0.9975 between the mean PID score of each RCB class; boxplot B.ii. produced a p value of 0.044 and an R2 correlation value of 0.9847 between the mean PID score of each RCB class