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Table 3 Platelet counts on day 14 reflect response and survival

From: Early recovery of the platelet count after decitabine-based induction chemotherapy is a prognostic marker of superior response in elderly patients with newly diagnosed acute myeloid leukaemia

 

PLT ≥ 60 × 109/L

(N = 42)

PLT < 60 × 109/L

(N = 75)

P

PLT ≥ 100 × 109/L

(N = 27)

PLT < 100 × 109/L

(N = 90)

P

ORR (%)

88.1

62.7

0.003

85.2

67.8

0.078

CR (%)

80.9

45.3

< 0.001

85.2

50

0.001

NR (%)

11.9

37.3

 

14.8

32.2

 

OS (months)

16.5

9.1

0.009

31

10.1

0.003

First CR

DFS (months)

16.3

7.4

0.024

16.9

8.9

0.006

  1. PLT platelet, CR complete remission, ORR overall response rate, NR no remission, OS overall survival, DFS disease-free survival