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Table 4 Multivariate analysis of prognostic factors in patients with venous thromboembolism (N = 51)

From: Early venous thromboembolism at the beginning of palliative chemotherapy is a poor prognostic factor in patients with metastatic pancreatic cancer: a retrospective study

 

Overall survival (OS)

Hazard ratio

95% CI

P-value

Time of VTE occurrence (early vs. late)

3.768

1.705–8.328

0.001

Khorana score (high-risk vs. intermediate-risk)

1.005

0.454–2.224

0.990

Number of metastatic organs (≥3 vs. < 3)

5.961

1.640–21.665

0.007

Hb (< 10 g/dL vs. ≥10 g/dL)

1.277

0.344–4.739

0.714

Na (< 135 mmol/L vs. ≥135 mmol/L)

0.913

0.334–2.496

0.859

Albumin (< 3.5 g/dL vs. ≥3.5 g/dL)

1.605

0.482–5.343

0.441

CA 19–9 (≥1000 U/mL vs. < 1000 U/mL)

1.74

0.920–3.289

0.088

Lung metastases (Yes vs. No)

1.822

0.909–3.651

0.091

  1. NLR neutrophil-to-lymphocyte ratio, Hb hemoglobin, CA19–9 cancer antigen 19–9; LN lymph node