Skip to main content

Table 1 Characteristics of patients (N = 216)

From: Early venous thromboembolism at the beginning of palliative chemotherapy is a poor prognostic factor in patients with metastatic pancreatic cancer: a retrospective study

 

No VTE

 

VTE

 

Total

P-value

N

%

N

%

N

Age, median (range)

  < 70 years

113

75.3

37

24.7

150

0.425

  ≥ 70 years

53

80.3

13

19.7

66

 

Sex

 Male

108

82.4

23

17.6

131

0.016

 Female

58

68.2

27

31.8

85

 

BSA

  < 1.8 m2

153

78.1

43

21.9

196

0.187

  ≥ 1.8 m2

13

65

7

35

20

 

BMI

  < 30 kg/m2

162

77.1

48

22.9

210

0.549

  ≥ 30 kg/m2

4

66.7

2

33.3

6

 

DM

 No

90

73.2

33

26.8

123

0.14

 Yes

76

81.7

17

18.3

93

 

Site of primary mass:

 Head

80

79.2

21

20.8

101

0.506

 Body

28

80

7

20

35

 

 Tail

58

72.5

22

27.5

80

 

Previous surgery:

 Palliative

10

83.3

2

16.7

12

0.584

 None

156

76.5

48

23.5

204

 

ECOG PS

 0–1

150

76.5

46

23.5

196

0.726

 2–3

16

80

4

20

20

 

WBC

  < 11,000/μL

136

75.1

45

24.9

181

0.174

  ≥ 11,000/μL

30

85.7

5

14.3

35

 

Hb

  < 10 g/dL

31

68.9

14

31.1

45

0.404

  ≥ 10 g/dL

193

74.8

65

25.2

258

 

PLT

     

0.091

  < 350,000/μL

148

78.7

40

21.3

188

 

  ≥ 350,000/μL

18

64.3

10

35.7

28

 

CA19–9

  < 1000 U/mL

88

75.2

29

24.8

117

0.535

  ≥ 1000 U/mL

78

78.8

21

21.2

99

 

Khorana score

 Intermediate–risk (2)

105

77.8

30

22.2

135

0.677

 High-risk (≥3)

61

75.3

20

24.7

81

 

CVC insertion

 No

32

69.6

14

30.4

46

0.219

 Yes

133

78.2

37

21.8

170

 

Chemotherapy more than first-line

  ≥ Second-line

68

81

16

19

84

0.205

 First-line only

88

72.7

33

27.3

121

 

 Unknown

10

90.9

1

9.1

11

 

Number of metastatic organs

  < 3

40

85.1

7

14.9

47

0.129

  ≥ 3

126

74.6

43

25.4

169

 
  1. BSA body surface area, BMI body mass index, DM diabetes mellitus, ECOG PS Eastern Cooperative Oncology Group Performance Status, WBC white blood cell, Hb hemoglobin, PLT platelet, CA19–9 cancer antigen 19–9, CVC, central venous catheter