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Table 3 The gene - gene interaction of XRCC1 and TP53 in the cervical cancer group and the negative control group

From: Interaction between TP53 and XRCC1 increases susceptibility to cervical cancer development: a case control study

  B SE Wald N P OR 95% CI
Recessive model
 XRCC1 −0.15 0.88 0.03 1 0.86 0.86 0.15 4.79
 Tp53 0.29 0.89 0.11 1 0.75 1.33 0.24 7.56
 Tp53-GG/GC by XRCC1-GG/GA −0.06 0.96 0.00 1 0.95 0.95 0.15 6.16
 常数 0 0.82 0 1 1 1   
Additive model
 Tp53    7.71 2 0.02*    
 Tp53-GC −1.10 0.40 7.69 1 0.01* 0.33 0.15 0.72
 Tp53-CC −0.41 0.51 0.64 1 0.42 0.67 0.25 1.80
 Tp53 * XRCC1    10.49 4 0.03*    
 Tp53-GC by XRCC1-GA 1.53 0.48 10.43 1 0.00* 4.63 1.83 11.75
 Tp53-GC by XRCC1-AA 0.80 0.58 1.93 1 0.17 2.23 0.72 6.92
 Tp53-CC by XRCC1-GA −0.10 0.64 0.02 1 0.88 0.91 0.26 3.20
 Tp53-CC by XRCC1-AA 0.11 0.94 0.01 1 0.91 1.11 0.18 6.97
 常数 0.30 0.22 1.93 1 0.17 1.35   
Dominant model
 XRCC1-GA/AA 0.71 0.27 6.84 1 0.01* 2.03 1.20 3.46
 Tp53-GC/CC −0.46 0.28 2.69 1 0.10 0.63 0.37 1.09
 常数 −0.02 0.25 0.01 1 0.93 0.98   
  1. *indicated p-value< 0.05