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Table 3 The gene - gene interaction of XRCC1 and TP53 in the cervical cancer group and the negative control group

From: Interaction between TP53 and XRCC1 increases susceptibility to cervical cancer development: a case control study

 

B

SE

Wald

N

P

OR

95% CI

Recessive model

 XRCC1

−0.15

0.88

0.03

1

0.86

0.86

0.15

4.79

 Tp53

0.29

0.89

0.11

1

0.75

1.33

0.24

7.56

 Tp53-GG/GC by XRCC1-GG/GA

−0.06

0.96

0.00

1

0.95

0.95

0.15

6.16

 常数

0

0.82

0

1

1

1

  

Additive model

 Tp53

  

7.71

2

0.02*

   

 Tp53-GC

−1.10

0.40

7.69

1

0.01*

0.33

0.15

0.72

 Tp53-CC

−0.41

0.51

0.64

1

0.42

0.67

0.25

1.80

 Tp53 * XRCC1

  

10.49

4

0.03*

   

 Tp53-GC by XRCC1-GA

1.53

0.48

10.43

1

0.00*

4.63

1.83

11.75

 Tp53-GC by XRCC1-AA

0.80

0.58

1.93

1

0.17

2.23

0.72

6.92

 Tp53-CC by XRCC1-GA

−0.10

0.64

0.02

1

0.88

0.91

0.26

3.20

 Tp53-CC by XRCC1-AA

0.11

0.94

0.01

1

0.91

1.11

0.18

6.97

 常数

0.30

0.22

1.93

1

0.17

1.35

  

Dominant model

 XRCC1-GA/AA

0.71

0.27

6.84

1

0.01*

2.03

1.20

3.46

 Tp53-GC/CC

−0.46

0.28

2.69

1

0.10

0.63

0.37

1.09

 常数

−0.02

0.25

0.01

1

0.93

0.98

  
  1. *indicated p-value< 0.05