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Table 2 The association between gene polymorphism of XRCC1 (rs25487), TP53(rs1042522) and cervical cancer

From: Interaction between TP53 and XRCC1 increases susceptibility to cervical cancer development: a case control study

Variable Groups Co-dominate model Recessive model
  P-value OR 95%CI P-value OR 95%CI
 rs25487 Cases vs NC G/A 0.00* 2.00 1.14–3.50 0.02* 2.54 1.15–5.59
A/A   3.43 1.50–7.85    
Cases vs OC G/A 0.03* 1.61 0.91–2.87 0.03* 2.40 1.06–5.46
A/A   3.00 1.26–7.10    
NC vs OC G/A 0.76 0.81 0.45–1.43 0.91 0.95 0.37–2.43
A/A   0.87 0.33–2.30    
 rs1042522 Cases vs NC G/C 0.54 0.73 0.41–1.29 0.82 0.92 0.47–1.82
C/C   0.78 0.37–1.64    
Cases vs OC G/C 0.41 0.88 0.48–1.59 0.21 0.66 0.34–1.27
C/C   0.61 0.30–1.27    
NC vs OC G/C 0.51 1.21 0.65–2.24 0.32 0.71 0.36–1.39
C/C   0.79 0.37–1.67    
Variable Groups Dominant model Allele model
P-value OR 95%CI P-value OR 95%CI
 rs25487 Cases vs NC 0.00* 2.30 1.37–3.86 0.00* 2.05 1.39–3.04
Cases vs OC 0.02* 1.88 1.10–3.22 0.00* 1.79 1.20–2.67
NC vs OC 0.47 0.82 0.48–1.40 0.53 0.87 0.57–1.34
 rs1042522 Cases vs NC 0.27 0.74 0.43–1.27 0.37 0.84 0.58–1.23
Cases vs OC 0.37 0.78 0.45–1.34 0.17 0.77 0.52–1.12
NC vs OC 0.87 1.05 0.59–1.86 0.64 0.91 0.62–1.34
  1. OR Odd ratio, CI Confidence interval, NC Negative controls, OC Elderly patients above the age of 80
  2. *indicated p-value< 0.05