TY - JOUR AU - Liu, Gui-Cen AU - Zhou, Yun-Fei AU - Su, Xiao-Chao AU - Zhang, Jun PY - 2019 DA - 2019/01/07 TI - Interaction between TP53 and XRCC1 increases susceptibility to cervical cancer development: a case control study JO - BMC Cancer SP - 24 VL - 19 IS - 1 AB - Cervical cancer is the 4th highest cause of female reproductive tract malignancies. Multiple loci have been identified as important determinant factors for tumor susceptibility. In this report, we aimed to explore the roles of gene polymorphisms affecting x-ray repair cross complementing 1 (XRCC1), the tumor protein p53 (TP53), and fibroblast growth factor receptor 3 (FGFR3) in the context of susceptibility to cervical cancer. Additionally, we assessed the impact of single nucleotide polymorphism-single nucleotide polymorphism (SNP-SNP) interaction of these three genes in the context of cervical cancer risk in Chinese women. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-018-5149-0 DO - 10.1186/s12885-018-5149-0 ID - Liu2019 ER -