All | Total T | Free T | |||||
---|---|---|---|---|---|---|---|
Low | Normal | p value | Low | Normal | p value | ||
Patients, no.(%) | 586(100) | 106(18.1) | 480(81.9) | 152(25.9) | 434(74.1) | ||
General information | |||||||
Age, no.(%) | < 0.001* | < 0.001* | |||||
< 70 | 297(50.7) | 25(23.6) | 272(56.7) | 51(33.6) | 246(56.7) | ||
≥ 70 | 289(49.3) | 81(76.4) | 208(43.3) | 101(66.4) | 188(43.3) | ||
Age, mean ± SD | 71.73 ± 6.19 | 66.80 ± 8.07 | < 0.001* | 70.26 ± 7.18 | 66.79 ± 8.06 | < 0.001* | |
BMI, mean ± SD | 23.54 ± 3.63 | 23.40 ± 3.57 | 0.803 | 23.95 ± 3.50 | 23.46 ± 3.60 | 0.153 | |
Diabetes, no.(%) | 0.018* | 0.049* | |||||
Absent | 480(81.9) | 78(73.6) | 402(83.8) | 116(76.3) | 364(83.9) | ||
Present | 106(18.1) | 28(26.4) | 78(16.2) | 36(23.7) | 70(16.1) | ||
Hypertension, no.(%) | 0.764 | 0.895 | |||||
Absent | 498(85.0) | 89(84.0) | 409(85.2) | 130(85.5) | 368(84.8) | ||
Present | 88(15.0) | 17(16.0) | 71(14.4) | 22(14.5) | 66(15.2) | ||
Coronary heart disease, no.(%) | 0.316 | 0.460 | |||||
Absent | 519(88.6) | 91(85.8) | 428(89.2) | 132(86.8) | 387(89.2) | ||
Present | 67(11.4) | 15(14.2) | 52(10.8) | 20(13.2) | 47(10.8) | ||
Smoking, no.(%) | 0.301 | 0.426 | |||||
Absent | 495(84.5) | 86(81.1) | 409(85.2) | 133(87.5) | 366(84.3) | ||
Present | 91(15.5) | 20(18.9) | 71(14.8) | 19(12.5) | 68(15.7) | ||
Alcohol consumption, no.(%) | 0.001* | 0.071 | |||||
Absent | 430(73.4) | 63(59.4) | 367(76.5) | 103(67.8) | 327(75.3) | ||
Present | 156(26.6) | 43(40.6) | 113(23.5) | 49(32.2) | 107(24.7) | ||
Pre-operative ED, no.(%) | < 0.001* | < 0.001* | |||||
ED absent | 376(64.2) | 44(41.5) | 332(69.2) | 76(50.0) | 300(69.1) | ||
ED present | 210(35.8) | 62(58.5) | 148(30.8) | 76(50.0) | 134(30.9) | ||
Pre-operative tumor characteristics | |||||||
PSA, no.(%) | < 0.001* | < 0.001* | |||||
< 10 ng/ml | 214(36.5) | 11(10.4) | 203(42.3) | 35(23.0) | 179(41.2) | ||
≥ 10 ng/ml | 372(63.5) | 95(89.6) | 277(57.7) | 117(77.0) | 255(58.8) | ||
PSA, mean ± SD | 16.34 ± 6.81 | 13.06 ± 6.90 | < 0.001* | 15.10 ± 6.92 | 13.14 ± 6.95 | < 0.001* | |
Proportion of free-PSA, no.(%) | 0.155 | 0.297 | |||||
< 0.16 | 419(71.5) | 82(77.4) | 337(70.2) | 114(75.0) | 305(70.3) | ||
≥ 0.16 | 167(28.5) | 24(22.6) | 143(29.8) | 38(25.0) | 129(29.7) | ||
Proportion of free-PSA, mean ± SD | 0.124 ± 0.060 | 0.139 ± 0.067 | 0.022* | 0.132 ± 0.070 | 0.137 ± 0.064 | 0.144 | |
Clinical tumor stage, no.(%) | < 0.001* | < 0.001* | |||||
T2a | 79(13.5) | 15(14.2) | 64(13.3) | 17(11.2) | 62(14.3) | ||
T2b | 154(26.3) | 20(18.9) | 134(27.9) | 26(17.1) | 128(29.5) | ||
T2c | 219(37.4) | 30(28.3) | 189(39.4) | 56(36.8) | 163(37.6) | ||
T3 | 134(22.9) | 41(38.7) | 93(19.4) | 53(34.9) | 81(18.7) | ||
Biopsy Gleason Score, no.(%) | < 0.001* | < 0.001* | |||||
6 | 143(24.4) | 10(9.4) | 133(27.7) | 16(10.5) | 127(29.3) | ||
7 | 295(50.3) | 52(49.1) | 243(50.6) | 76(50.0) | 219(50.5) | ||
8 or higher | 148(25.3) | 44(41.5) | 104(21.7) | 60(39.5) | 88(20.3) | ||
Post-operative information | |||||||
Surgical approach, no.(%) | 0.067 | 0.257 | |||||
Open | 272(46.4) | 58(54.7) | 214(44.6) | 77(50.7) | 195(44.9) | ||
Laparoscopic | 314(53.6) | 48(45.3) | 266(55.4) | 75(49.3) | 239(55.1) | ||
NVB preserve, no.(%) | 0.913 | 0.771 | |||||
Not preserved | 224(38.2) | 41(38.7) | 183(38.1) | 60(39.5) | 164(37.8) | ||
Preserved | 362(61.8) | 65(61.3) | 297(61.9) | 92(60.5) | 270(62.2) | ||
Pathological tumor stage, no.(%) | 0.006* | < 0.001* | |||||
T2a | 76(13.0) | 13(12.3) | 63(13.1) | 13(8.6) | 63(14.5) | ||
T2b | 150(25.6) | 18(17.0) | 132(27.5) | 28(18.4) | 122(28.1) | ||
T2c | 180(30.7) | 28(26.4) | 152(31.7) | 41(27.0) | 139(32.0) | ||
T3 | 180(30.7) | 47(44.3) | 133(27.7) | 70(46.1) | 110(25.3) | ||
Final Gleason Score, no.(%) | < 0.001* | < 0.001* | |||||
6 | 126(21.5) | 10(9.4) | 116(24.2) | 11(7.2) | 115(26.5) | ||
7 | 259(44.2) | 23(21.7) | 236(49.2) | 47(30.9) | 212(48.8) | ||
8 or higher | 201(34.3) | 73(68.9) | 128(26.7) | 94(61.8) | 107(24.7) | ||
Seminal invasion, no.(%) | 0.022* | 0.026* | |||||
Absent | 563(96.1) | 97(91.5) | 466(97.1) | 141(92.8) | 422(97.2) | ||
Present | 23(3.9) | 9(8.5) | 14(2.9) | 11(7.2) | 12(2.8) | ||
PSM, no.(%) | 0.128 | 0.094 | |||||
Absent | 536(91.5) | 93(87.7) | 443(92.3) | 134(88.2) | 402(92.6) | ||
Present | 50(8.5) | 13(12.3) | 37(7.7) | 18(11.8) | 34(7.8) | ||
Lymph node status, no.(%) | 0.003* | 0.001* | |||||
N- | 225(38.4) | 52(49.1) | 173(36.0) | 68(44.7) | 157(36.2) | ||
Nx | 336(57.3) | 46(43.4) | 290(60.4) | 71(46.7) | 265(61.1) | ||
N+ | 25(4.3) | 8(7.5) | 17(3.6) | 13(8.6) | 12(2.8) | ||
Post-operative ED, no.(%) | 0.001* | < 0.001* | |||||
ED absent | 197(33.6) | 13(12.3) | 184(38.3) | 22(14.5) | 175(40.3) | ||
ED present | 179(30.5) | 31(29.2) | 148(30.8) | 54(35.5) | 125(28.8) | ||
Post-operative incontinence, no.(%) | 0.506 | 0.662 | |||||
Absent | 511(87.2) | 94(88.7) | 417(86.9) | 134(88.2) | 377(86.9) | ||
Present | 69(11.8) | 10(9.4) | 59(12.3) | 16(10.5) | 53(12.2) |