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Fig. 2 | BMC Cancer

Fig. 2

From: KRas4B-PDE6δ complex stabilization by small molecules obtained by virtual screening affects Ras signaling in pancreatic cancer

Fig. 2

Identification and evaluation on the cellular viability of the compounds with greater interaction energy on the interprotein region compared with the effect of Deltarasin. Evaluation of 38 compounds at 200 μM, Deltarasin at 5 μM and DMSO as vehicle, on the MIA PaCa-2 (a, c, e, g, i and k) and hTERT-HPNE (b, d, f, h, j and l) cell lines

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