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Fig. 1 | BMC Cancer

Fig. 1

From: KRas4B-PDE6δ complex stabilization by small molecules obtained by virtual screening affects Ras signaling in pancreatic cancer

Fig. 1

Interaction of ligands that stabilize the KRas4B-PDE6δ molecular complex in silico. The interprotein surface of interaction marked with gray color was used for the accomplishment of docking, being this the region with greater contact between KRas4B GTPase (pink and yellow) and PDE6δ (blue). The compounds D14 (black) and C22 (aqua) were identified in the same inter-protein interactions sites. (Molecular Operating Environment (MOE), 2014.09)

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BMC Cancer

ISSN: 1471-2407

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