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Table 4 Impact of ELR and ENLR on overall survival (OS): Kaplan-Meier survival analysis, univariate and multivariate Cox regression (models for ELR and ENLR, respectively) in high-risk patients (ESMO-ESGO-ESTRO groups 4–6, n = 91)

From: New pre-treatment eosinophil-related ratios as prognostic biomarkers for survival outcomes in endometrial cancer

Variables Kaplan-Meier survival analysis UNIVARIATE Cox regression MULTIVARIATE Cox regression for ELR ≥ 0.1 model MULTIVARIATE Cox regression for ENLR ≥0.5 model
X2 p-value HR (IC 95%) p-value HR (IC 95%) p-value HR (IC 95%) p-value
Age ≥ 65 years (vs. <  65 years) 6.9 0.008 3.7 (1.3–10.5) 0.014 3.2 (1.03–10.3) 0.045 3.2 (1.1–9.7) 0.038
FIGO advanced stage III (vs. stage I-II) 2.2 0.135 2.1 (0.8–5.7) 0.143 2.6 (0.8–8.6) 0.109 2.5 (0.8–7.7) 0.104
Tumour grade 3 (vs. grade 1–2) 6.7 0.010 5.6 (1.3–24.5) 0.022 6.9 (1.5–31.6) 0.013 5.8 (1.3–26.3) 0.023
Endometroid histology (vs. other histology) 1.7 0.194 0.5 (0.2–1.4) 0.202 0.5 (0.2–1.5) 0.195 0.5 (0.2–1.6) 0.257
ELR ≥ 0.1 (vs. < 0.1) 3.9 0.047 3.3 (1.3–8.7) 0.014 4.6 (1.7–12.5) 0.002
ENLR ≥0.5 (vs. <  0.5) 5.4 0.020 3.0 (1.1–7.7) 0.026 3.9 (1.6–9.8) 0.011
  1. All entries in boldface reflect p-values < 0.05