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Table 4 Impact of ELR and ENLR on overall survival (OS): Kaplan-Meier survival analysis, univariate and multivariate Cox regression (models for ELR and ENLR, respectively) in high-risk patients (ESMO-ESGO-ESTRO groups 4–6, n = 91)

From: New pre-treatment eosinophil-related ratios as prognostic biomarkers for survival outcomes in endometrial cancer

Variables

Kaplan-Meier survival analysis

UNIVARIATE Cox regression

MULTIVARIATE Cox regression for ELR ≥ 0.1 model

MULTIVARIATE Cox regression for ENLR ≥0.5 model

X2

p-value

HR (IC 95%)

p-value

HR (IC 95%)

p-value

HR (IC 95%)

p-value

Age ≥ 65 years (vs. <  65 years)

6.9

0.008

3.7 (1.3–10.5)

0.014

3.2 (1.03–10.3)

0.045

3.2 (1.1–9.7)

0.038

FIGO advanced stage III (vs. stage I-II)

2.2

0.135

2.1 (0.8–5.7)

0.143

2.6 (0.8–8.6)

0.109

2.5 (0.8–7.7)

0.104

Tumour grade 3 (vs. grade 1–2)

6.7

0.010

5.6 (1.3–24.5)

0.022

6.9 (1.5–31.6)

0.013

5.8 (1.3–26.3)

0.023

Endometroid histology (vs. other histology)

1.7

0.194

0.5 (0.2–1.4)

0.202

0.5 (0.2–1.5)

0.195

0.5 (0.2–1.6)

0.257

ELR ≥ 0.1 (vs. < 0.1)

3.9

0.047

3.3 (1.3–8.7)

0.014

4.6 (1.7–12.5)

0.002

ENLR ≥0.5 (vs. <  0.5)

5.4

0.020

3.0 (1.1–7.7)

0.026

3.9 (1.6–9.8)

0.011

  1. All entries in boldface reflect p-values < 0.05