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Table 3 Impact of ELR and ENLR on overall survival (OS): Kaplan Meier survival analysis, univariate and multivariate Cox regression (models for ELR and ENLR, respectively), n = 163

From: New pre-treatment eosinophil-related ratios as prognostic biomarkers for survival outcomes in endometrial cancer

Variables Kaplan-Meier survival analysis UNIVARIATE Cox regression MULTIVARIATE Cox regression for ELR ≥ 0.1 model MULTIVARIATE Cox regression for ENLR ≥0.5 model
X2 p-value HR (IC 95%) p-value HR (IC 95%) p-value HR (IC 95%) p-value
Age ≥ 65 years (vs. <  65 years) 3.9 0.047 2.6 (0.98–6.7) 0.055 2.8 (1.0–8.2) 0.059 2.8 (1.03–7.8) 0.043
FIGO advanced stage III (vs. stage I-II) 8.3 0.004 3.4 (1.4–8.4) 0.007 3.1 (0.9–9.8) 0.060 2.8 (0.9–8.5) 0.065
Tumour grade 3 (vs. grade 1–2) 15.8 0.000 8.1 (2.4–27.4) 0.001 6.8 (1.9–24.7) 0.003 5.8 (1.6–21.2) 0.007
Endometroid histology (vs. other histology) 10.1 0.001 0.3 (0.1–0.63) 0.003 0.4 (0.1–1.1) 0.068 0.4 (0.14–1.2) 0.099
ESMO-ESTRO-ESGO High Risk groups 4–6 (vs. groups 1–3) 7.4 0.007 4.7 (1.4–15.8) 0.014 1.2 (0.2–6.5) 0.856 1.3 (0.2–6.9) 0.770
ELR ≥ 0.1 (vs. < 0.1) 6.3 0.004 2.9 (1.2–6.8) 0.017 4.9 (1.9–12.4) 0.001
ENLR ≥ 0.5 (vs. <  0.5) 6.6 0.010 3.0 (1.2–7.3) 0.015 3.9 (1.6–9.8) 0.003
  1. All entries in boldface reflect p-values < 0.05