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Fig. 6 | BMC Cancer

Fig. 6

From: MEF2 plays a significant role in the tumor inhibitory mechanism of encapsulated RENCA cells via EGF receptor signaling in target tumor cells

Fig. 6

RENCA macrobeads modulate the expression of MEF2 isoforms through EGF receptor signaling. MEF2A, MEF2B, MEF2C and MEF2D expression was assessed by qRT-PCR on (a) DU145 or (b) DU145/GR cells cultured in naïve media or together with > 18 wk. RENCA macrobeads alone or pre-treated with 1 μM gefitinib followed by culture in media as described for 5 days. MEF2B expression was not detected in DU145 or DU145/GR cells. Each column represents the mean (n = 3) ± SD. *p < 0.005, compared with naïve media or gefitinib in naïve media

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BMC Cancer

ISSN: 1471-2407

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