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Fig. 3 | BMC Cancer

Fig. 3

From: MEF2 plays a significant role in the tumor inhibitory mechanism of encapsulated RENCA cells via EGF receptor signaling in target tumor cells

Fig. 3

RENCA macrobeads regulate the epidermal growth factor receptor in both murine and human cell lines. In-cell Western analysis of total EGFR, phosphorylated EGFR (pY1068) and overlay (normalized pY1068/EGFR) in (a) RENCA cells, and (b) DU145 cells following exposure to 5-day conditioned media (CM) from RENCA macrobeads at 1–2 weeks or > 18 weeks of age as indicated. Cells cultured in naïve media were used as a control. Each column represents the mean normalized intensity in arbitrary units (AU) (n = 6–8) ± SD. *p < 0.001, compared with naïve media

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