Fig. 3From: MEF2 plays a significant role in the tumor inhibitory mechanism of encapsulated RENCA cells via EGF receptor signaling in target tumor cellsRENCA macrobeads regulate the epidermal growth factor receptor in both murine and human cell lines. In-cell Western analysis of total EGFR, phosphorylated EGFR (pY1068) and overlay (normalized pY1068/EGFR) in (a) RENCA cells, and (b) DU145 cells following exposure to 5-day conditioned media (CM) from RENCA macrobeads at 1–2 weeks or > 18 weeks of age as indicated. Cells cultured in naïve media were used as a control. Each column represents the mean normalized intensity in arbitrary units (AU) (n = 6–8) ± SD. *p < 0.001, compared with naïve mediaBack to article page