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Fig. 1 | BMC Cancer

Fig. 1

From: Microsatellite instability test using peptide nucleic acid probe-mediated melting point analysis: a comparison study

Fig. 1

Maximum sensitivity evaluation of PNA and MNR method. The maximum sensitivity of PNA and MNR methods was evaluated using mixed samples of genomic DNA samples obtained from HeLa (MSS) and SNU-638 (MSI-H) cells. a PNA method was capable of detecting alteration in all five MSI marker genes in samples containing down to 5% MSI-H variant. b MNR method required at least 20% MSI-H variant in samples to detect alteration in all five MSI marker genes

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