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Table 1 Patient and tumor characteristics for the derivation and validation sets

From: Non-linear transformations of age at diagnosis, tumor size, and number of positive lymph nodes in prediction of clinical outcome in breast cancer

Factor

Derivation set

Validation set

No of patients

4477

1132

Distant recurrences a

1315 (29)b

289 (26)

Age median, years

60

64

Age range, years

25–93

28–99

 Age < 35

69 (2)

11 (1)

 Age 35–50

1023 (23)

202 (18)

 Age > 50

3385 (76)

919 (81)

Tumor size median, mm

22

20

Tumor size range, mm

1–120

1–160

 T1 (≤20 mm)

1942 (43)

590 (52)

 T2 (21–50 mm)

2460 (55)

506 (45)

 T3 (> 50 mm)

75 (2)

36 (3)

Lymph nodes median

1

0

Lymph nodes range

0–47

0–23

 Negative

1783 (40)

659 (58)

 1–3 positive

1781 (40)

305 (27)

 4–9 positive

649 (14)

127 (11)

 ≥ 10 positive

264 (6)

41 (4)

Adjuvant medical treatment

 Endocrine therapy

2662 (59)

673 (59)

 Chemotherapy

460 (10)

52 (5)

 Chemo-endocrine

74 (2)

38 (3)

 None

1279 (29)

369 (33)

 Missing

2

0

  1. aFollow-up truncated at 10 years
  2. bNumbers in parentheses are percentages