Skip to main content

Table 2 Cox regression analysis of prognostic factors for HCC patients

From: SKA1 overexpression is associated with poor prognosis in hepatocellular carcinoma

Variables OS RFS
Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
HR (95% CI) P HR (95% CI) P HR (95% CI) P HR (95% CI) P
Gender(male/female) 1.355 (0.537–3.416) 0.520    1.621 (0.652–4.031) 0.299   
Age (> 53/≤53 years) 1.446 (0.827–2.527) 0.195    1.990 (1.970–2.011) 0.454   
Tumor size (> 5/≤5 cm) 2.275 (1.296–3.994) 0.004    2.603 (1.583–4.281) 0.001   
Differentiation (poor/well to moderate) 1.835 (0.954–3.530) 0.069    1.213 (0.721–2.040) 0.466   
HBsAg (positive/negative) 1.323 (0.526–3.328) 0.552    1.147 (0.524–2.509) 0.731   
AFP (≥200/< 200 μg/L) 1.000 (1.081–3.281) 0.025 1.395 (0.782–2.489) 0.260 1.912 (1.183–3.090) 0.008 1.449 (0.857–2.450) 0.167
TNM stage (III + IV/I + II) 1.516 (1.156–1.987) 0.003 1.962 (1.196–3.684) 0.031 1.688 (1.337–3.131) 0.001 1.472 (1.131–1.916) 0.004
SKA1 expression (positive/negative) 2.497 (1.380–4.516) 0.002 2.133 (1.145–3.974) 0.017 1.974 (1.208–3.224) 0.007 1.750 (1.064–2.878) 0.028
  1. AFP, α-fetoprotein; CI, confidence interval, HBsAg; hepatitis B virus surface antigen; HCC, hepatocellular carcinoma; HR, hazard ratio; OS, overall survival; RFS, relapse-free survival
\