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Table 1 Demographic characteristics of the 2 cohorts according to the EGFR-TKI mutation subtypes

From: Different mutational characteristics of the subsets of EGFR-tyrosine kinase inhibitor sensitizing mutation-positive lung adenocarcinoma

    SNV* E19del** P-value
Study cohort (n = 71) Age   62.58 ± 9.67 58.03 ± 9.95 0.0547‡‡
Gender Male 14 11 0.6822§
  Female 22 24  
Smoking history Ever smoker 11 9 0.8497§
  None smoker 25 26  
Stage I 22 12 0.1100§
  II 5 12  
  III 8 10  
  IV 1 1  
LUAD cohort (n = 47) §§ Age   66.56 ± 9.18 65.81 ± 10.40 0.8138‡‡
Gender Male 7 4 0.9234§
  Female 10 14  
Smoking history Ever smoker 15 4 0.0540§
  None smoker 13 15  
Stage I 13 7 0.9715§
  II 7 5  
  III 6 5  
  IV 1 1  
  1. * Study cohort of SNV subgroup includes one L861Q variant and LUAD cohort of SNV subgroup includes 3 cases of L861Q, 2 G719A, and 1 G719C variant
  2. **Includes E19 inframe del variants including LREA motif
  3. Includes 2 cases with double primary tumor
  4. ‡‡ P-values were obtained by independent sample t-test
  5. § P-values were obtained by chi-square test
  6. §§The clinical information of 2 cases is not available
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