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Table 1 Demographic characteristics of the 2 cohorts according to the EGFR-TKI mutation subtypes

From: Different mutational characteristics of the subsets of EGFR-tyrosine kinase inhibitor sensitizing mutation-positive lung adenocarcinoma

   

SNV*

E19del**

P-value

Study cohort (n = 71)†

Age

 

62.58 ± 9.67

58.03 ± 9.95

0.0547‡‡

Gender

Male

14

11

0.6822§

 

Female

22

24

 

Smoking history

Ever smoker

11

9

0.8497§

 

None smoker

25

26

 

Stage

I

22

12

0.1100§

 

II

5

12

 
 

III

8

10

 
 

IV

1

1

 

LUAD cohort (n = 47) §§

Age

 

66.56 ± 9.18

65.81 ± 10.40

0.8138‡‡

Gender

Male

7

4

0.9234§

 

Female

10

14

 

Smoking history

Ever smoker

15

4

0.0540§

 

None smoker

13

15

 

Stage

I

13

7

0.9715§

 

II

7

5

 
 

III

6

5

 
 

IV

1

1

 
  1. * Study cohort of SNV subgroup includes one L861Q variant and LUAD cohort of SNV subgroup includes 3 cases of L861Q, 2 G719A, and 1 G719C variant
  2. **Includes E19 inframe del variants including LREA motif
  3. † Includes 2 cases with double primary tumor
  4. ‡‡ P-values were obtained by independent sample t-test
  5. § P-values were obtained by chi-square test
  6. §§The clinical information of 2 cases is not available
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BMC Cancer

ISSN: 1471-2407

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