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Table 2 IC50 values of the isolated canine and human melanoma cell lines, 72 h after treatment with Dacarbazine, Vemurafenib and LY294002 (IC50 ± SEM, n = 6)

From: Isolation and characterization of two canine melanoma cell lines: new models for comparative oncology

IC50 (μM)
  A375 Sk-Mel28 Ocr_OCMM1X Ocr_OCMM2X
Dacarbazine 202.4 ± 60,40 261.04 ± 31.55 > 400 > 400
Vemurafenib 0.54 ± 0.05 10.78 ± 3.29 37.44 ± 8.84 12.31 ± 0.85
LY294002 61.63 ± 16.85 26.56 ± 0.81 37.74 ± 9.6 32.39 ± 2.01