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Table 1 Group differences in clinical characteristics and neuropsychological assessment

From: Investigation of chemotherapy-induced brain structural alterations in breast cancer patients with generalized q-sampling MRI and graph theoretical analysis

Characteristic Patients Treated After Chemotherapy (n = 19) Healthy Controls (n = 20) P
Mean or Count SD Mean or Count SD  
Age (years) 43.8 6.4 50.1 2.5 0.001
Education (years) 13.9 2.2 13.3 2.3 0.435
Breast cancer stage (0, I, II, III, IV) (0, 2, 14, 3, 0) N/A N/A N/A N/A
Chemotherapeutic drugs (Taxotere and Epirubicin) 19 N/A N/A N/A N/A
Radiation therapy 4 N/A N/A N/A N/A
Hormonal treatment 1 N/A N/A N/A N/A
Menopausal 5 N/A 5 N/A N/A
MMSE 28 1.283 28.316 1.453 0.508
CAMS-R 33.882 4.471 33.895 3.972 0.993
IES-R 15.941 24.055 7.079 10.498 0.187
Hospital Anxiety and Depression Scale (HADS)
 Anxiety 7.118 5.075 6.474 3.485 0.666
 Depression 3.941 3.842 5.474 2.702 0.184
Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog)
 Perceived cognitive impairments 52.588 10.319 58.789 7.522 0.052
 Comments from others 13.765 2.438 14.158 1.954 0.606
 Perceived cognitive abilities 17.882 4.523 18 5.4 0.946
 Impact on quality of life 11.765 3.557 14.211 1.989 0.023
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