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Fig. 8 | BMC Cancer

Fig. 8

From: Deletion of the murine ortholog of the 8q24 gene desert has anti-cancer effects in transgenic mammary cancer models

Fig. 8

The association of MYC and FAM84B gene copy number increase and overexpression with clinical outcomes in 2509 primary breast cancers of the METABRIC data set. (a) Frequency of MYC and FAM84B copy number amplification in 35 cancer types from the TCGA bioportal database. (b) (c) Oncoprint showing cases from the METABRIC data with MYC or FAM84B gene amplification (b) or gene expression greater than 2 standard deviations (SD) above the mean (c). (d) (e) Overall survival plots from the cancer bioportal for METABRIC breast cancer cases with (red plot) or without (blue plot) FAM84B (d) or MYC (e) gene overexpression (> 2 SD)

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