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Fig. 4 | BMC Cancer

Fig. 4

From: Deletion of the murine ortholog of the 8q24 gene desert has anti-cancer effects in transgenic mammary cancer models

Fig. 4

Modulation of tumorigenesis in the MMTV-neu transgenic model for human luminal HER2+ breast cancer. (a) Disease-free survival curves for MMTV-neu;MD+/+ (n = 19), MMTV-neu;MD+/− (n = 11) and MD−/− (n = 11) mice. Log-rank test P-values are shown. (b) Average age at the appearance of the first palpable tumor. (c) Tumor growth plot graphing average diameter size (in mm) versus weeks after first appearance. (d) Average age at end point. (e) Average amount of lung macro-metastatic foci. * = p < 0.05

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