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Fig. 2 | BMC Cancer

Fig. 2

From: Flavonoids modulate multidrug resistance through wnt signaling in P-glycoprotein overexpressing cell lines

Fig. 2

a and b. Wnt, GSK 3β and β-catenin mRNA and protein expression pattern in KB3–1 and KBCHR8–5 cell lines. Protein (Western blot) and mRNA (qRT-PCR) expression status of Wnt, GSK 3β, LRP6, FZD1, APC and axin in KBCHR8–5 cells. (c) theaflavin, (d) quercetin, (e) rutin, (f) epicatechin 3 gallate (E3G) and (g) tamarixetin. The protein levels were quantified by LI-COR Image Studio tool. The data denote means ± SD from three experiments. The protein expressions were normalized to the β-actin expression level. Gene expression was normalized with 18S and depicts quantification of three independent experiments (means ± S.D). Symbols not sharing a common symbol vary significantly at p ≤ 0.05 (DMRT)

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