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Table 1 Characteristic features of the experimental rats

From: Acyclic retinoid and angiotensin-II receptor blocker exert a combined protective effect against diethylnitrosamine-induced hepatocarcinogenesis in diabetic OLETF rats

Rat LETO OLETF
Treatment Vehicle Vehicle ACR ARB ACR + ARB
Body weight (g) 410.0 ± 21.6 498.0 ± 27.3a 491.7 ± 33.4a 493.8 ± 32.9a 480.0 ± 25.0a
Triglyceride (mg/dL) 18.0 ± 4.0 83.8 ± 16.0a 74.0 ± 10.8ab 60.3 ± 2.0ab 59.0 ± 11.1ab
Glucose (mg/dL) 174.3 ± 17.1 199.6 ± 26.6a 189.8 ± 13.9a 184.2 ± 12.6a 184.3 ± 19.2a
Insulin (μU/ml) 8.5 ± 2.8 33.2 ± 13.1a 29.9 ± 22.3a 35.4 ± 24.3a 33.6 ± 15.0a
AST (IU/L) 216.7 ± 10.6 239.6 ± 41.4a 232.9 ± 32.0a 237.4 ± 50.9a 242.8 ± 44.2a
ALT (IU/L) 51.5 ± 2.0 73.9 ± 14.4a 66.4 ± 8.4a 67.1 ± 11.1a 74.3 ± 6.9a
Albumin (g/mL) 3.85 ± 0.15 4.11 ± 0.09 3.93 ± 0.11 3.87 ± 0.13 4.02 ± 0.1
Total bilirubin (mg/dL) 0.100 ± 0.02 0.103 ± 0.02 0.093 ± 0.017 0.095 ± 0.012 0.079 ± 0.017
  1. Data presented as mean ± standard deviation (SD) values. Each group comprises 10 rats. a: p < 0.05 vs. LETO with vehicle group. B: p < 0.05 vs. OLETF with vehicle group