Skip to main content

Table 1 Characteristic features of the experimental rats

From: Acyclic retinoid and angiotensin-II receptor blocker exert a combined protective effect against diethylnitrosamine-induced hepatocarcinogenesis in diabetic OLETF rats

Rat

LETO

OLETF

Treatment

Vehicle

Vehicle

ACR

ARB

ACR + ARB

Body weight (g)

410.0 ± 21.6

498.0 ± 27.3a

491.7 ± 33.4a

493.8 ± 32.9a

480.0 ± 25.0a

Triglyceride (mg/dL)

18.0 ± 4.0

83.8 ± 16.0a

74.0 ± 10.8ab

60.3 ± 2.0ab

59.0 ± 11.1ab

Glucose (mg/dL)

174.3 ± 17.1

199.6 ± 26.6a

189.8 ± 13.9a

184.2 ± 12.6a

184.3 ± 19.2a

Insulin (μU/ml)

8.5 ± 2.8

33.2 ± 13.1a

29.9 ± 22.3a

35.4 ± 24.3a

33.6 ± 15.0a

AST (IU/L)

216.7 ± 10.6

239.6 ± 41.4a

232.9 ± 32.0a

237.4 ± 50.9a

242.8 ± 44.2a

ALT (IU/L)

51.5 ± 2.0

73.9 ± 14.4a

66.4 ± 8.4a

67.1 ± 11.1a

74.3 ± 6.9a

Albumin (g/mL)

3.85 ± 0.15

4.11 ± 0.09

3.93 ± 0.11

3.87 ± 0.13

4.02 ± 0.1

Total bilirubin (mg/dL)

0.100 ± 0.02

0.103 ± 0.02

0.093 ± 0.017

0.095 ± 0.012

0.079 ± 0.017

  1. Data presented as mean ± standard deviation (SD) values. Each group comprises 10 rats. a: p < 0.05 vs. LETO with vehicle group. B: p < 0.05 vs. OLETF with vehicle group