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Table 4 A detailed overview of DNA copy number gains or losses in primary tumors and metastatic tissues

From: Genomic alterations in gastric cancers discovered via whole-exome sequencing

Unique to the primary tumor tissues
Locating Gene Locus V CN Locating Gene Locus V CN
 ACSL3, PAX3 2q36.1 + 3.49 MAD2L1BP 6p21.1 + 2.69
 BRCA1 17q21.31 + 3.79 MSH6, FBXO11 2p16.3 + 3.21
 BRCA2, KL 13q13.1 + 2.66 MTCP1 Xq28 + 3.62
 CCNB1IP1 14q11.2 + 3.31 MTUS2, FLT1 13q12.3 + 2.66
 CCND1 11q13.3 + 5.83 MYB 6q23.3 + 6.07
 CDK12 17q12 + 6.5 NCOA4 10q11.23 + 2.93
 CDK8 13q12.13 + 2.66 NIN 14q22.1 + 3.44
 CDX2, FLT3 13q12.2 + 2.66 NOTCH2 1p11.2 + 4.68
 EGFR 7p11.2 + 4.54 NRAS, TRIM33 1p13.2 + 4.68
 ELK4, IKBKE, SLC45A3 1q32.1 + 2.74 PDE4DIP 1q21.1 + 7.66
 EPCAM, MSH2 2p21 + 3.21 RABEP1, USP6 17p13.2 + 2.82
 ERBB2 17q12 + 3.76~ 6.5 RARA, TOP2 17q21.2 + 3.76~ 6.5
 ERBB4, IDH1 2q34 + 2.86 RB1 13q14.2 + 2.64
 ERCC5 13q33.1 + 2.64 SMAD2 18q21.1 + 3.53
 FAM46C, HSD3B2 1p12 + 4.68 STAT3 17q21.2 + 3.79
 FEV, ATIC 2q35 + 2.08~ 3.49 SUZ12 17q11.2 + 2.71
 FGFR3 4p16.3 + 4.21 TERT 5p15.33 + 3.03
 KRT17 17q21.2 + 3.08 TRIM27 6p22.1 + 2.97
 KTN1 14q22.3 + 3.44 YWHAE 17p13.3 + 4.21
 LCP1 13q14.13 + 2.64 ZMYM2 13q12.11 + 2.66
 LRP5 11q13.2 + 5.83 ZRSR2 Xp22.2 + 3.23
Unique to the metastatic tissues
Locating Gene Locus V CN Locating Gene Locus V CN
CHD6, MAFB, TOP1 20q12 + 3.05 SRC 20q11.23 + 3.05
NUMA1 11q13.4 + 2.94     
Common to the primary tumor and metastasis tissues
Locating Gene Locus V CN Locating Gene Locus V CN
HIP1 7q11.23 + 2.65~ 2.77 RAD51B 14q24.1 + 2.75–2.78
CHIC2, KDR, KIT, PDGFRA 4q12 + 2.67~ 3.17 ETV4 17q21.31 + 2.66–5.11
TMPRSS2 21q22.3 + 2.90~ 3.88 CDKN2A 9p21.3 0.8–1.32
PMS2 7p22.1 + 2.62~ 2.78 CDKN2B 9p21.3 0.8–1.32
  1. V CNV state, CN Copy number, +, CNV gain; —, CNV loss
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