Table 3 Summary of CNV types and numbers in primary tumor and metastatic samples of 5 patients
From: Genomic alterations in gastric cancers discovered via whole-exome sequencing
ID | Num (S-Gain) | Num (S-Loss) | Num (L-Gain) | Num (L-Loss) | |
P1 | 113 | 39 | 61 | 4 | |
P2 | 791 | 446 | 9 | 70 | |
P3 | 1241 | 19 | 238 | 1 | |
P4 | 1093 | 5 | 395 | 25 | |
P5 | 22 | 109 | 131 | 82 | |
Total | 3260 | 618 | 834 | 182 | |
Status | Num | Main locus | CN | ||
Unique | S-Gain | 2601 | 1p12; 1p13; 1q21; 1q23; 1q32; 1q42; 11q13; 13q12; 13q11; 13q22; 13q32; 13q33; 14q21; 14q22; 5p12;17p13; 17q21; 5p13; 5p15; 6p21; 6p22; 7q11; Xp22 | 2~ 16.67 | |
S-Loss | 332 | 4q32; 4q33; 4q35; 9p21; 9p22; 9p23; 9p24; 11p15; 16p13; 18p11 | 0.52~ 2 | ||
L-Gain | 580 | 1p11; 1q21; 10p12; 10q11; 11q13; 12p13; 14q32; 15q13; 16p13; 17q11; 20q11; 20q11; 20q13 | 2~ 7.04 | ||
L-Loss | 47 | 1q21; 10q11; 16p13; 2p24; 22q11; 8p23 | 0.41~ 2 | ||
Common | S-Gain L-Gain | 279 | 1q21; 11q13; 14q24; 17p13; 17q12; 17q21; 17q24; 19p13; ap23; 21q22; 4q12; 7p22; 7q11; 8p23; 9p12; 9q12; 9p13; 9q31; | 2.00~ 7.04 | |
S-Loss L-Loss | 52 | 1q21; 10q11; 11p11; 11q12; 15q24; 16p13; 16p12; 17q12; 2q13; 14q11; 22q11; 5q13; 1p36; 5q35; 6p21; 8p23; 9p21; 9p12; 9p11.2 | 0.11~ 1.42 | ||
S-Loss L-Gain | 1 | 7q22.1 | 0.91~ 1.12 3.42~ 7.04 | ||