Table 3 Hazard ratios (95% CI) of colon, rectal, and colorectal cancers by physical activity level at baseline and follow-up (n = 79,184) in the NOWAC Study

Cancer

Models

1–2

3–4

5–6

7–8

9–10

p trend

 Colon

Age-adjusted

N of cases = 833

0.85 (0.61–1.19)

37

0.96 (0.81–1.14)

199

1.00

379

0.81 (0.68–0.97)

182

0.83 (0.59–1.17)

36

0.10

Multivariable 1

N of cases = 818

0.79 (0.56–1.11)

36

0.94 (0.79–1.12)

196

1.00

371

0.84 (0.70–1.00)

180

0.81 (0.57–1.15)

35

0.23

Multivariable 2

N of cases = 818

0.78 (0.55–1.10)

36

0.94 (0.79–1.12)

196

1.00

371

0.84 (0.70–1.01)

180

0.82 (0.58–1.16)

35

0.27

 Rectal

Age-adjusted

N of cases = 398

1.22 (0.79–1.88)

23

0.90 (0.69–1.17)

82

1.00

173

0.87 (0.67–1.12)

92

1.36 (0.92–2.03)

28

0.85

Multivariable 1

N of cases = 390

1.24 (0.80–1.93)

23

0.90 (0.68–1.17)

80

1.00

170

0.85 (0.66–1.10)

89

1.37 (0.91–2.04)

28

0.90

Multivariable 2

N of cases = 390

1.22 (0.78–1.89)

23

0.88 (0.67–1.15)

80

1.00

170

0.86 (0.66–1.11)

89

1.40 (0.93–2.09)

28

0.74

 Colorectal

Age-adjusted

N ofcases = 1231

0.96 (0.74–1.26)

60

0.94 (0.81–1.09)

281

1.00

552

0.83 (0.72–0.96)

269

1.00 (0.78–1.30)

63

0.22

Multivariable 1

N ofcases = 1208

0.92 (0.70–1.21)

59

0.93 (0.80–1.08)

276

1.00

541

0.84 (0.73–0.98)

269

0.99 (0.76–1.29)

63

0.36

Multivariable 2

N ofcases = 1208

0.91 (0.69–1.19)

59

0.92 (0.80–1.09)

276

1.00

541

0.85 (0.73–0.98)

269

1.00 (0.77–1.30)

63

0.47