Fig. 6
From: Porcine circovirus type 2 ORF3 protein induces apoptosis in melanoma cells
Tumor growth in enhanced in RGS KO mice. a Bioluminescence imaging of B16F10-luc subcutaneous grafts in WT and RGS16 KO mice at 8 days post-injection. Total flux (radiance) of the ROI (region of interest) of WT = 4229 · 105 (p/s, photons per second). Total flux of the ROI of RGS16 KO = 2111 · 107 p/s. Exposure time 3 min. b Melanoma graft tumor weight (g), isolated from female C57BL6 WT mice (n = 10) and RGS16 KO mice (n = 10) 21 days after cell engraftment. The difference in tumor weight between WT and RGS16 KO mice was statistically significant (p < 0.05) regardless of vast individual variability