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Fig. 5 | BMC Cancer

Fig. 5

From: Porcine circovirus type 2 ORF3 protein induces apoptosis in melanoma cells

Fig. 5

Tumor growth is inhibited by ORF3 in WT and RGS16 KO mice. a Growth dynamics of B16F10 tumor wild-type (WT) mice (dark columns, n = 6) or in RGS16 KO (light columns, n = 6), treated with pcDNA3.1. b Growth dynamics of B16F10 tumor in wild-type mice (dark, n = 6) or RGS16 KO mice (light, n = 6), treated with pcDNA-ORF3. The length and width of the tumor were measured in the direction of the latitude with an accuracy of 0.5 mm using a digital caliper and calculated as described in material and methods section. In the Y axes are shown melanoma volume V (cm3), calculated according to Feldman [18]. Error bars indicate standard deviation

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