Fig. 3From: Prevalence of drug-drug interactions in oncology patients enrolled on National Clinical Trials Network oncology clinical trialsBreakdown of protocol guidance detected drug-drug interactions by patient and their clinical relevance. Patients were screened for drug-drug interactions based on protocol guidance to exclude, avoid or use medications with caution. Interactions were examined for clinical relevance by patient, and then further examined if they would impact study agent efficacy or toxicity. A total of 10.2% patients (n = 13) were taking a concomitant medication that was suggested to use with caution or avoid with the study agent, and 3.1% (n = 4) had a clinically relevant interaction. DDI = drug-drug interactionBack to article page