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Table 3 ORsa and 95% CIs for low (defined as values below the scale-specific median) HRQOL scales according to sociodemographic and clinical characteristics in CRC survivors (n = 1294) from cross-sectional analyses

From: Health-related quality of life in long-term survivors of colorectal cancer and its association with all-cause mortality: a German cohort study

Characteristics

n

Summary score < median

Global QOL < median

Physical functioning scale <median

Role functioning scale <median

Emotional functioning scale <median

Social functioning scale <median

Cognitive functioning scale <median

OR (95% CI)b

OR (95% CI)b

OR (95% CI)b

OR (95% CI)b

OR (95% CI)b

OR (95% CI)b

OR (95% CI)b

Sex

 Male

740

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Female

554

1.19 (0.94–1.51)

0.95 (0.75–1.21)

1.65 (1.29–2.11)

0.96 (0.75–1.22)

1.01 (0.80–1.27)

0.61 (0.48–0.78)

0.78 (0.62–0.99)

Age, years

 < 60

192

1.31 (0.93–1.86)

1.21 (0.85–1.71)

0.85 (0.60–1.21)

1.21 (0.85–1.72)

1.38 (0.98–1.96)

1.46 (1.02–2.10)

1.19 (0.85–1.68)

 60–69

520

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

 70–79

479

1.21 (0.94–1.57)

1.20 (0.93–1.56)

1.70 (1.31–2.22)

1.15 (0.89–1.49)

0.97 (0.75–1.25)

0.77 (0.59–1.01)

1.29 (1.00–1.66)

 ≥ 80

103

1.58 (1.00–2.49)

1.85 (1.15–2.96)

3.91 (2.34–6.52)

2.07 (1.30–3.29)

0.89 (0.57–1.39)

0.58 (0.36–0.94)

1.85 (1.17–2.91)

Education

 Low

597

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Middle

393

0.99 (0.76–1.30)

0.68 (0.52–0.89)

0.96 (0.73–1.26)

0.95 (0.73–1.25)

0.95 (0.73–1.23)

1.09 (0.82–1.43)

1.04 (0.80–1.35)

 High

292

0.86 (0.64–1.16)

0.58 (0.43–0.78)

0.67 (0.49–0.91)

0.87 (0.64–1.17)

0.89 (0.66–1.19)

0.75 (0.55–1.02)

0.79 (0.59–1.06)

Family status

 Single

52

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Married/in partnership

991

0.96 (0.54–1.72)

0.87 (0.49–1.57)

0.73 (0.40–1.34)

0.86 (0.48–1.54)

0.98 (0.55–1.74)

1.14 (0.63–2.09)

1.16 (0.65–2.07)

 Divorced

65

1.35 (0.63–2.89)

0.98 (0.46–2.09)

0.99 (0.45–2.18)

0.97 (0.45–1.08)

0.97 (0.46–2.05)

1.09 (0.49–2.41)

1.21 (0.57–2.55)

 Widowed

147

0.97 (0.50–1.89)

1.14 (0.58–2.24)

0.67 (0.33–1.37)

0.82 (0.42–1.60)

0.94 (0.49–1.82)

1.02 (0.51–2.06)

1.38 (0.71–2.67)

Tumor location

 Colon

613

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Rectum

552

1.11 (0.84–1.45)

1.02 (0.77–1.33)

1.33 (1.01–1.76)

1.28 (0.98–1.69)

1.03 (0.79–1.35)

1.41 (1.07–1.86)

0.90 (0.68–1.17)

 Both

58

1.95 (1.08–3.54)

1.48 (0.82–2.68)

1.39 (0.77–2.53)

1.23 (0.69–2.19)

0.83 (0.47–1.45)

1.19 (0.66–2.16)

1.14 (0.65–2.02)

Metastases

 No

872

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Yes

209

1.43 (1.02–2.01)

1.11 (0.79–1.55)

1.29 (0.91–1.83)

1.04 (0.74–1.46)

1.14 (0.81–1.59)

1.47 (1.03–2.10)

1.33 (0.95–1.86)

Other Cancer

 No

997

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Yes

270

1.39 (1.05–1.85)

1.38 (1.03–1.83)

1.32 (0.99–1.77)

1.38 (1.04–1.84)

1.03 (0.78–1.37)

1.60 (1.20–2.15)

1.35 (1.02–1.79)

Therapy

 None

681

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Chemotherapy

285

0.90 (0.66–1.23)

1.03 (0.75–1.40)

1.13 (0.82–1.56)

1.07 (0.78–1.47)

0.90 (0.66–1.23)

1.21 (0.88–1.68)

0.93 (0.68–1.27)

 Radiation

40

1.02 (0.52–1.99)

1.59 (0.79–3.20)

0.89 (0.44–1.82)

0.89 (0.45–1.76)

0.66 (0.34–1.29)

1.74 (0.87–3.50)

0.75 (0.38–1.46)

 Chemotherapy + Radiation

268

1.56 (1.11–2.18)

1.57 (1.12–2.20)

0.96 (0.68–1.35)

1.62 (1.16–2.27)

1.04 (0.74–1.45)

2.33 (1.64–3.31)

1.33 (0.96–1.85)

Current stoma

 No

1130

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Yes

151

1.11 (0.76–1.62)

1.30 (0.88–1.92)

2.13 (1.42–3.20)

1.87 (1.27–2.77)

1.46 (1.00–2.14)

2.44 (1.60–3.71)

1.03 (0.71–1.50)

  1. Abbreviations: BMI Body mass index, CI Confidence interval, CRC Colorectal cancer, HRQOL Health-related quality of life, MET Metabolic equivalent hours of task, OR Odds ratio, QOL Quality of life, Ref Reference
  2. aCalculated with a multivariable-adjusted logistic regression model
  3. bAdjusted for sex, age at HRQOL assessment, BMI, physical activity, tumor location, metastases, other cancer, therapy, and stoma; except the exposure variable of interest