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Table 1 All depicted samples were analyzed on transcriptional level with massive parallel sequencing (IonTorrent); *samples additionally analyzed with digital probe-based technology (NanoString)

From: RNA-based analysis of ALK fusions in non-small cell lung cancer cases showing IHC/FISH discordance

IHC-negative/FISH-negative

IHC-negative/FISH-BL-negative (10–14%)

IHC-negative/FISH-BL-positive (15–20%)

IHC-negative/FISH-positive (> 30%)

IHC-positive/FISH-BL-positive (15–20%)

IHC-positive/FISH-positive

P01

P27*

P22*

P31*

P19* (IHC uncertain)

P13*

P02*

P28*

P23*

P32*

P20*

P14*

P03*

P29*

P24*

P33*

P21*

P15*

P04*

P30*

P25*

  

P16*

P05*

 

P26*

  

P17

P06

    

P18

P07

     

P08

     

P09

     

P10

     

P11

     

P12

     

N = 12

N = 4

N = 5

N = 3

N = 3

N = 6

33 samples