Long-term survival and late complications of intensity-modulated radiotherapy for recurrent nasopharyngeal carcinoma

Table 5 Impact of prognostic factors on treatment results by multivariate analysis (p value)

Factors	LRFS	DMFS	OS
Age (years)
< 60 vs. ≥60	–	0.970	0.106
rT stage
rT1–2 vs. rT3–4	0.918	0.463	0.315
FD (Gy)
≤ 2 vs. > 2	0.137	–	0.686
Use of Chem
No vs. Yes	0.610	0.009	0.342
TTR (years)
≤ 2 vs. > 2	0.964	0.041	–
IMRT dose (Gy)
< 70 vs. ≥70	0.575	–	–
Cumulative dose (Gy)
< 140 vs. ≥140	–	0.117	0.112
Brachytherapy
No vs. Yes	0.051	–	–

Abbreviations: LRFS, local recurrence–free survival; DMFS, distant metastases–free survival; OS, overall survival; FD, Fractional dose; Chem, chemotherapy; TTR, time to recurrence

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