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Table 4 Univariate analysis of potential prognostic factors

From: Long-term survival and late complications of intensity-modulated radiotherapy for recurrent nasopharyngeal carcinoma

Items 3-yr LRFS 3-yr DMFS 3-yr OS
  % p % p % p
Gender
 Male 90.1 0.356 89.3 0.387 41.8 0.980
 Female 83.1 91.8 47.6
Age (years)
 < 60 84.9 0.884 89.0 0.070 51.0 0.026
 ≥ 60 87.2 100 32.4
rT stage
 rT1–2 96.6 0.070 94.7 0.362 51.8 0.241
 rT3–4 77.9 88.8 42.9
FD (Gy)
 ≤ 2 81.6 0.298 90.3 0.820 45.5 0.645
 > 2 94.0 93.2 47.4
Use of Chem
 No 88.8 0.433 83.2 0.328 49.0 0.196
 Yes 83.8 93.9 45.1
TTR (years)
 ≤ 2 91.7 0.248 83.9 0.035 43.6 0.977
 > 2 82.1 94.8 47.0
IMRT dose (Gy)
 < 70 85.6 0.790 93.6 0.908 42.8 0.652
 ≥ 70 84.7 86.1 54.0
Cumulative dose(Gy)
 < 140 85.5 0.508 88.3 0.118 49.2 0.095
 ≥ 140 88.0   96.2   41.0  
Brachytherapy
 No 79.1 0.027 90.6 0.887 44.6 0.495
 Yes 100   94.4   57.9  
  1. Abbreviations: LRFS, local recurrence–free survival; DMFS, distant metastases–free survival; OS, overall survival; FD, Fractional dose; Chem, chemotherapy; TTR, time to recurrence