Overview of the pathological results and treatment characteristics in the first 1000 patients randomized in the SERC trial: axillary dissection versus no axillary dissection in patients with involved sentinel node

Table 7 Multivariate analysis of factors associated with NSN involvement in patients treated by radiotherapy and without chemotherapy prior to ALND

Effect	P value	Contrast	Odd Ratio Estimate	95% CI	P value
Age in class	0.2626	41–75 vs > 75	1.402	[0.409; 4.805]	0.5905
Age in class		<=40 vs > 75	0.256	[0.023; 2.887]	0.2702
Tumor Size	0.9233	10–30 vs < =10	0.842	[0.273; 2.598]	0.7644
Tumor Size		> 30 vs < =10	0.982	[0.226; 4.263]	0.9807
LVI	0.3089	Pos. Vs Neg.	0.682	[0.326; 1.425]	0.3089
Capsular Effraction	0.0381	Yes vs No	2.357	[1.048; 5.302]	0.0381
Hormonal receptors	0.4821	Pos. Vs Neg.	1.647	[0.410; 6.617]	0.4821
HER2 Status	0.1906	Pos. Vs Neg.	0.376	[0.087; 1.626]	0.1906
Histology Type	0.5892	Mixed/Other vs lobular	0.478	[0.111; 2.047]	0.3196
Histology Type		Ductal vs lobular	0.665	[0.243; 1.818]	0.4267
SBR Grade	0.0650	Gr II vs Gr I	3.332	[1.214; 9.143]	0.0195
SBR Grade		Gr III vs Gr I	2.714	[0.831; 8.862]	0.0982
Nb Involved SN	0.1171	> 2 vs < =2	6.797	[0.618; 74.708]	0.1171
SN Status	0.3734	Macro vs ITC	3.737	[0.451; 30.991]	0.2219
SN Status		Micro vs ITC	2.635	[0.305; 22.767]	0.3784

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