Fig. 1From: TRPM7 overexpression enhances the cancer stem cell-like and metastatic phenotypes of lung cancer through modulation of the Hsp90α/uPA/MMP2 signaling pathwayTRPM7 is aberrantly expressed in lung cancer tissue samples and cell lines. a Image showing that TRPM7 is strongly expressed in lung adenocarcinoma and squamous cell carcinoma, in comparison to weak expression in normal alveoli. b TRPM7 mRNA expression is upregulated in lung tumor tissues, compared to non-tumor tissues. c Compared to normal lung epithelial 16-HBE cell, TRPM7 protein expression level is upregulated in SPCA-1, NCI-H520, SK-MES-1, A549 and 95D lung cancer cell lines. β-actin served as loading control. *p < 0.05, **p < 0.01, ***p < 0.001Back to article page