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Table 3 Univariate analysis between the two groups of patients, after setting the NLR cutoff value at 4.7

From: Neutrophils to lymphocytes ratio as a useful prognosticator for stage II colorectal cancer patients

Parameter NLR ≤ 4.7 (n = 260) NLR > 4.7 (n = 36) p-value
Gender
 Female 96 18 NS
 Male 164 18
Age (years)
 Median + IR 71 (63–77) 75.5 (70.5–81) 0.004
Age > 72
 Age  72 144 13 0.033
 Age > 72 116 23
Primary tumor
 Right colon 88 15 NS
 Left colon 54 8
 Rectum 118 13
Differentiation
 Low 56 7 NS
 Medium + High 204 29
Τ
 T1 17 1 NS
 T2 49 8
 T3 175 20
 T4 19 7
Ν
 N0 165 22 NS
 N1 68 9
 N2 27 5
No of lymph nodes harvested
 Median + IR 19 (14–27) 17 (15–28) NS
No of lymph nodes harvested
 Lymph nodes ≥12 230 31 NS
 Lymph nodes < 12 30 5
Stage
 Stage I 55 6 NS
 Stage II 110 16
 Stage III 95 14
Perineural invasion
 No 246 27 < 0.001
 Yes 14 9
Vascular invasion
 No 226 27 NS
 Yes 34 9
Lymphatic invasion
 No 227 30 NS
 Yes 33 6
Site of recurrence
 Distant 12 4 NS
 Local 14 1
Follow up
 Alive with recurrence 8 0 0.036
 Deaths related to the recurrence 18 5
 Deaths unrelated to the disease 35 10
 Alive 199 21
Probability for overall survival
 Alive 204 21 0.012
 Dead 56 15
Probability for recurrence
 No recurrence 234 31 NS
 Recurrence 26 5
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